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hello my name is avery fulford and today

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i'll be discussing my senior thesis

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entitled a comparative genomic analysis

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of the 250 million year old halophilic

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archaeon halo simplex carlsbadency

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so in the year 2000 four organisms were

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extracted from 250 million year old salt

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crystals in new mexico by vreeland at

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all

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one of these samples has been named as a

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novel species named halo simplex

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carlsbadency which is a halophilic

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archaeon or a microbe adapted to extreme

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salinity

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we aligned and compared the genome of

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this organism to its 17 most closely

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related halophiles to identify the

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adaptations involved in its long-term

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survival

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we found that dna repair membrane

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transport and oxidative stress response

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mechanisms are required for long-term

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salt entrapment

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dna repair combats the rearrangement of

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pyrimidine bonds by hypersalinity

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membrane transport proteins protect

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against hypertonic conditions and

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oxidative stress response mechanisms